A lecture and laboratory course dealing with the immune response of vertebrates with special emphasis on mammalian systems. The development and anatomy of the immune system, as well as the various cellular components (leukocytes) and proteins (cytokines, antibodies, complement proteins) are studied in detail. Topics covered include antigen presentation, T and B cell function, immunoglobulin structure and function, innate and acquired immune responses, granulocyte mediated responses, immunity to pathogens, various forms of hypersensitivity including allergies and autoimmune diseases, and applied topics such as transplantation immunity. Labs deal with induction and measurement of an immune response. Prerequisite: “C” or better in BIOL 244.